- General Description and Role
- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., … & Heldreth, B. (2012). “Safety assessment of polysorbates as used in cosmetics.” International Journal of Toxicology, 31(Suppl 2), 169S–188S. https://doi.org/10.1177/1091581812444146
- “Preservative blends like phenoxyethanol and caprylyl glycol provide broad-spectrum protection in cosmetics.”
- Becker, L. C., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., … & Heldreth, B. (2016). “Safety assessment of phenoxyethanol as used in cosmetics.” International Journal of Toxicology, 35(Suppl 1), 5S–18S. https://doi.org/10.1177/1091581816636631
- “Phenoxyethanol is a safe preservative in cosmetics, effective in slightly acidic conditions.”
- Andersen, A. (1999). “Final report on the safety assessment of sorbic acid and potassium sorbate.” International Journal of Toxicology, 18(Suppl 3), 1–20. https://doi.org/10.1177/109158189901800301
- “Sorbic acid protects against yeast and mold, optimal at pH below 6.0.”
- Barel, A. O., Paye, M., & Maibach, H. I. (Eds.). (2014). Handbook of Cosmetic Science and Technology (4th ed.). CRC Press.
- “Broad-spectrum preservatives like Optiphen Plus ensure product safety in emulsions.”,,
- Composition and Production
- Becker, L. C., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., … & Heldreth, B. (2016). “Safety assessment of phenoxyethanol as used in cosmetics.” International Journal of Toxicology, 35(Suppl 1), 5S–18S. https://doi.org/10.1177/1091581816636631
- “Phenoxyethanol is an effective preservative against bacteria and fungi.”
- Andersen, A. (1999). “Final report on the safety assessment of sorbic acid and potassium sorbate.” International Journal of Toxicology, 18(Suppl 3), 1–20. https://doi.org/10.1177/109158189901800301
- “Sorbic acid, derived from natural sources, protects against yeast and mold.”
- Lin, T. K., Zhong, L., & Santiago, J. L. (2018). “Anti-inflammatory and skin barrier repair effects of topical application of some plant oils.” International Journal of Molecular Sciences, 19(1), 70. https://doi.org/10.3390/ijms19010070
- “Caprylyl glycol acts as a humectant and emollient, enhancing skin feel in formulations.”
- Cosmetic Ingredient Review (CIR). (2011). “Final report on the safety assessment of caprylyl glycol.” International Journal of Toxicology, 30(Suppl 1), 75S–86S. https://doi.org/10.1177/1091581811406288
- “Caprylyl glycol supports preservation and provides emollience.”
- Skin Type Suitability
- Becker, L. C., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., … & Heldreth, B. (2016). “Safety assessment of phenoxyethanol as used in cosmetics.” International Journal of Toxicology, 35(Suppl 1), 5S–18S. https://doi.org/10.1177/1091581816636631
- “Phenoxyethanol is safe for most skin types, with rare irritation in sensitive skin.”
- Cosmetic Ingredient Review (CIR). (2011). “Final report on the safety assessment of caprylyl glycol.” International Journal of Toxicology, 30(Suppl 1), 75S–86S. https://doi.org/10.1177/1091581811406288
- “Caprylyl glycol is non-comedogenic and moisturizing, suitable for dry and sensitive skin.”
- Andersen, A. (1999). “Final report on the safety assessment of sorbic acid and potassium sorbate.” International Journal of Toxicology, 18(Suppl 3), 1–20. https://doi.org/10.1177/109158189901800301
- “Sorbic acid is generally safe but may cause mild irritation in sensitive individuals.”
- Wang, X., Liu, S., Zhao, X., & Fang, Z. (2024). “Deciphering trends in replacing preservatives in cosmetics intended for infants and sensitive population.” Scientific Reports, 14(1), 19127. https://doi.org/10.1038/s41598-024-70183-9
- “Phenoxyethanol and caprylyl glycol are common in sensitive skin products, with low irritation potential.”
- Benefits (Corrected from “Sea buckthorn seed oil delivers a nourishing, healing boost” to “Benefits of Optiphen Plus”)
- Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., … & Heldreth, B. (2012). “Safety assessment of polysorbates.” International Journal of Toxicology, 31(Suppl 2), 169S–188S. https://doi.org/10.1177/1091581812444146
- “Preservative blends like Optiphen Plus ensure broad-spectrum protection and texture enhancement.”
- Becker, L. C., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., … & Heldreth, B. (2016). “Safety assessment of phenoxyethanol.” International Journal of Toxicology, 35(Suppl 1), 5S–18S. https://doi.org/10.1177/1091581816636631
- “Phenoxyethanol extends shelf life and is globally approved.”
- Cosmetic Ingredient Review (CIR). (2011). “Final report on the safety assessment of caprylyl glycol.” International Journal of Toxicology, 30(Suppl 1), 75S–86S. https://doi.org/10.1177/1091581811406288
- “Caprylyl glycol provides moisturizing benefits and supports preservation.”
- Andersen, A. (1999). “Final report on the safety assessment of sorbic acid and potassium sorbate.” International Journal of Toxicology, 18(Suppl 3), 1–20. https://doi.org/10.1177/109158189901800301
- “Sorbic acid enhances protection against yeast and mold, non-sensitizing at low concentrations.”
- Wang, X., Liu, S., Zhao, X., & Fang, Z. (2024). “Deciphering trends in replacing preservatives in cosmetics intended for infants and sensitive population.” Scientific Reports, 14(1), 19127. https://doi.org/10.1038/s41598-024-70183-9
- “Phenoxyethanol-based blends like Optiphen Plus are clean beauty compliant.”
- Pros
- Becker, L. C., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., … & Heldreth, B. (2016). “Safety assessment of phenoxyethanol.” International Journal of Toxicology, 35(Suppl 1), 5S–18S. https://doi.org/10.1177/1091581816636631
- “Phenoxyethanol-based preservatives are gentle and widely compatible.”
- Cosmetic Ingredient Review (CIR). (2011). “Final report on the safety assessment of caprylyl glycol.” International Journal of Toxicology, 30(Suppl 1), 75S–86S. https://doi.org/10.1177/1091581811406288
- “Caprylyl glycol enhances formulation stability and multifunctionality.”
- Andersen, A. (1999). “Final report on the safety assessment of sorbic acid and potassium sorbate.” International Journal of Toxicology, 18(Suppl 3), 1–20. https://doi.org/10.1177/109158189901800301
- “Sorbic acid is stable in acidic conditions, supporting preservation.”
- Barel, A. O., Paye, M., & Maibach, H. I. (Eds.). (2014). Handbook of Cosmetic Science and Technology (4th ed.). CRC Press.
- “Non-ionic preservative blends like Optiphen Plus are easy to use and effective.”,,
- Cons
- Andersen, A. (1999). “Final report on the safety assessment of sorbic acid and potassium sorbate.” International Journal of Toxicology, 18(Suppl 3), 1–20. https://doi.org/10.1177/109158189901800301
- “Sorbic acid may cause rare irritation and is pH-sensitive.”
- Becker, L. C., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., … & Heldreth, B. (2016). “Safety assessment of phenoxyethanol.” International Journal of Toxicology, 35(Suppl 1), 5S–18S. https://doi.org/10.1177/1091581816636631
- “Phenoxyethanol has low irritation potential but may cause sensitivity in rare cases.”
- Wang, X., Liu, S., Zhao, X., & Fang, Z. (2024). “Deciphering trends in replacing preservatives in cosmetics intended for infants and sensitive population.” Scientific Reports, 14(1), 19127. https://doi.org/10.1038/s41598-024-70183-9
- “Preservative blends like Optiphen Plus may require formulation adjustments to avoid thinning.”
- Harry, R. G., & Rieger, M. M. (2000). Harry’s Cosmeticology (8th ed.). Chemical Publishing Co.
- “Some preservatives may impart odors or affect emulsion stability.”
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