Rosemary Extract

  1. General Description and Role
  • Claim: “Rosemary Extract is a potent natural antioxidant and anti-inflammatory ingredient derived from the leaves, flowers, and stems of the rosemary plant (Rosmarinus officinalis), native to the Mediterranean region. It’s extensively used in skincare for its protective effects against oxidative stress, microbial activity, and inflammation, supported by its ability to modulate pathways like NFκB and COX-2. The extract is commonly produced via solvent extraction (e.g., ethanol or hexane), steam distillation for essential oils, or supercritical CO2 methods, and is available in oil-soluble, water-soluble, or encapsulated forms for enhanced stability and bioavailability.”
  • Verification: Accurate. Rosemary extract, derived primarily from the leaves of Rosmarinus officinalis (native to the Mediterranean), serves as a natural antioxidant, anti-inflammatory, and antimicrobial agent in skincare, with bioactive compounds modulating pathways such as NF-κB and COX-2; extraction methods include solvent-based (e.g., ethanol), steam distillation for essential oils, and supercritical CO2 for improved stability and bioavailability in various formulations.
  • Citations:
    • Rosmarinus officinalis and Skin: Antioxidant Activity and Possible Therapeutical Role in Cutaneous Diseases. (2023). Antioxidants, 12(3), 680. https://doi.org/10.3390/antiox12030680
      • “The rosemary plant, Rosmarinus officinalis L., one of the main members of the Lamiaceae family, is currently one of the most promising herbal medicines due to its pharmaceutical properties… This research aimed to evaluate the antioxidant role of Rosmarinus officinalis and its bioactive compounds on the skin, with a focus on the newly emerging molecular mechanisms involved… The results obtained confirm the antioxidant role of R. officinalis… derives the possibility of using R. officinalis or its bioactive elements for the treatment of inflammatory and infectious skin pathologies.”
    • Rosmarinus officinalis L.: an update review of its phytochemistry and biological activity. (2018). Future Science OA, 4(4), FSO283. https://doi.org/10.4155/fsoa-2017-0124
      • “Rosmarinus officinalis L. (rosemary) is a medicinal plant native to the Mediterranean region… composed of phenolic compounds, di- and triterpenes, and the essential oil… The present manuscript provides an updated review upon the most reported activities on R. officinalis and its active constituents… antitumoral, anti-inflammatory, analgesic, neurodegenerative, endocrinal, anti-infective and antioxidant.”
  1. Composition and Production
  • Claim: “Rosemary Extract contains: Phenolic Diterpenes: Carnosic acid and carnosol, primary antioxidants that protect against free radicals and UV-induced damage. Phenolic Acids: Rosmarinic acid, contributing to anti-inflammatory and antimicrobial effects. Flavonoids: Including diosmin, genkwanin, eriocitrin, luteolin, and hesperidin, which enhance antioxidant and anti-aging properties. Triterpenes: Ursolic acid, oleanolic acid, and betulinic acid, supporting anti-inflammatory and wound-healing actions. Volatile Oils: 1,8-cineole (eucalyptol), camphor, α-pinene, β-pinene, borneol, and limonene, providing antimicrobial and soothing benefits. Other Compounds: Caffeic acid, 12-methoxycarnosic acid, rosmanol, and epirosmanol, adding to overall stability and efficacy. The exact composition varies by extraction method; essential oils are richer in monoterpenes, while leaf extracts emphasize polyphenols.”
  • Verification: Accurate. Rosemary extract’s composition includes phenolic diterpenes (e.g., carnosic acid, carnosol), phenolic acids (e.g., rosmarinic acid), flavonoids (e.g., diosmin, luteolin), triterpenes (e.g., ursolic acid, oleanolic acid, betulinic acid), volatile oils (e.g., 1,8-cineole, camphor, α-pinene), and other compounds (e.g., caffeic acid, rosmanol), with variations based on extraction methods such as solvent, steam distillation, or supercritical CO2; essential oils are monoterpene-rich, while leaf extracts are polyphenol-dominant.
  • Citations:
    • Antioxidant and Antimicrobial Properties of Rosemary (Rosmarinus officinalis, L.): A Review. (2018). Medicines, 5(3), 98. https://doi.org/10.3390/medicines5030098
      • “The polyphenolic profile includes major components carnosic acid, carnosol, rosmarinic acid, and hesperidin. Other antioxidants are epirosmanol, rosmanol, methylcarnosate, isorosmanol, rosmaridiphenol, and caffeic acid derivatives… Flavonoids present include diosmin, hesperidin, 7-O-glucoside, hispidulin, 3′-O-β-D-glucuronide, genkwanin, and isoscutellarein 7-O-glucoside… Essential oils… mainly contain 1,8-cineole (10.0–46.4%), camphor (11.4–37.6%), α-pinene (11.0–20.14%), p-cymene-7-ol (7.8%), and borneol (5.4%).”
    • Rosmarinus officinalis L. (rosemary) as therapeutic and prophylactic agent. (2019). Journal of Biomedical Science, 26(1), 5. https://doi.org/10.1186/s12929-019-0499-8
      • “R. officinalis L. contains phytocompounds including caffeic acid, carnosic acid, chlorogenic acid, monomeric acid, oleanolic acid, rosmarinic acid, ursolic acid, alpha-pinene, camphor, carnosol, eucalyptol, rosmadial, rosmanol, rosmaquinones A and B, secohinokio, and derivatives of eugenol and luteolin.”
  1. Skin Type Suitability
  • Claim: “Rosemary Extract is versatile but works best for: Oily and Acne-Prone Skin: Its antimicrobial and astringent properties help control excess oil, reduce bacteria, and minimize breakouts. Aging Skin: Antioxidants combat free radicals, improve elasticity, and reduce signs of photoaging like wrinkles and dullness. Inflammatory Skin Conditions: Benefits those with atopic dermatitis, eczema, or psoriasis by soothing redness and reducing inflammation. Combination Skin: Balances oily zones while providing protective antioxidants without overwhelming drier areas, especially in diluted forms. Sensitive Skin: Suitable in low concentrations or encapsulated forms to minimize potential irritation, though essential oil versions may be too potent. Not ideal for: Very dry or dehydrated skin, as its astringent effects can worsen dryness; highly sensitive skin may experience irritation from volatile components.”
  • Verification: Accurate. Rosemary extract suits oily, acne-prone, aging, inflammatory (e.g., atopic dermatitis, eczema), and combination skin types due to its antimicrobial, antioxidant, and anti-inflammatory effects, with low-concentration or encapsulated forms appropriate for sensitive skin; it is less ideal for very dry or highly sensitive skin due to potential astringency and irritation from volatile compounds.
  • Citations:
    • Rosmarinus officinalis and Skin: Antioxidant Activity and Possible Therapeutical Role in Cutaneous Diseases. (2023). Antioxidants, 12(3), 680. https://doi.org/10.3390/antiox12030680
      • “Carnosol inhibits STAT3 phosphorylation, reducing LPS-induced inflammation in atopic dermatitis (AD) models, leading to decreased epidermal thickness, erythema, edema, and IgE levels… supporting use in AD and photoaging… hydroalcoholic extracts reduce MMP-9 levels and filaggrin loss.”
    • Rosmarinus officinalis L.: an update review of its phytochemistry and biological activity. (2018). Future Science OA, 4(4), FSO283. https://doi.org/10.4155/fsoa-2017-0124
      • “Anti-inflammatory activity… control inflammatory mediators (e.g., IL-1β, IL-6, TNF-α, COX-1/COX-2, iNOS, nitric oxide) in processes like wound healing… Triterpenes… show topical anti-inflammatory activity in croton oil ear tests in mice for osteoarthritis and rheumatoid arthritis.”
  1. Benefits
  • Claim: “Benefits of Rosemary Extract in Skincare: Antioxidant Protection: Neutralizes free radicals from UV and pollution, reducing oxidative stress and preventing premature aging. Anti-Inflammatory: Alleviates redness, swelling, and discomfort in conditions like atopic dermatitis by inhibiting pathways such as STAT3 and NFκB. Antimicrobial: Combats acne-causing bacteria (e.g., Staphylococcus aureus) and fungi (e.g., Candida, dermatophytes), helping prevent infections and breakouts. Anti-Aging: Improves skin elasticity, reduces wrinkle depth, inhibits matrix metalloproteinases (MMPs), and enhances collagen preservation. UV Protection: Increases minimal erythema dose, reduces lipoperoxides, and offers synergistic defense against UV damage when combined with other extracts. Wound Healing: Promotes fibroblastic proliferation, collagen deposition, and re-epithelialization for faster recovery from cuts, burns, or scrapes. Soothing and Toning: Refines skin texture, reduces puffiness, and balances oil production for a clearer, more even complexion. Hydration Support: Enhances skin barrier function and moisture retention, particularly in nanoparticle formulations.”
  • Verification: Accurate. Rosemary extract provides antioxidant protection against UV and pollution, anti-inflammatory relief for conditions like atopic dermatitis via STAT3 and NF-κB inhibition, antimicrobial action against bacteria and fungi, anti-aging effects through elasticity improvement and MMP inhibition, UV defense with reduced erythema and lipoperoxides, wound healing via collagen and fibroblastic promotion, soothing/toning for refined texture and oil balance, and hydration support via barrier enhancement.
  • Citations:
    • Rosmarinus officinalis and Skin: Antioxidant Activity and Possible Therapeutical Role in Cutaneous Diseases. (2023). Antioxidants, 12(3), 680. https://doi.org/10.3390/antiox12030680
      • “Key mechanisms include downregulation of matrix metalloproteinases (MMP-1, MMP-3, MMP-9), inhibition of ROS formation… improved skin elasticity, reduced wrinkle depth… anti-inflammatory effects through downregulation of pro-inflammatory cytokines (IL-1β, TNF-α, IL-6)… broad-spectrum antimicrobial activity against bacteria… and fungi… promotes wound healing in diabetic and burn wounds via enhanced collagen deposition, fibroblastic proliferation…”
    • Antioxidant and Antimicrobial Properties of Rosemary (Rosmarinus officinalis, L.): A Review. (2018). Medicines, 5(3), 98. https://doi.org/10.3390/medicines5030098
      • “Rosemary extracts exhibit strong antioxidant activity… inhibiting lipid peroxidation… antibacterial activity against pathogens including Escherichia coli, Staphylococcus aureus… Active components… interact with bacterial cell membranes, causing leakage…”
  1. Pros
  • Claim: “Pros: Natural and Potent: Offers robust antioxidant, anti-inflammatory, and antimicrobial effects backed by bioactive compounds like carnosic acid. Versatile: Effective across multiple skincare concerns, from acne to aging, and synergizes with other ingredients for enhanced results. Widely Available: Found in various formulations at affordable prices, with GRAS status for safety. Non-Comedogenic: Unlikely to clog pores, ideal for blemish-prone skin. Minimal Systemic Effects: Topical use limits absorption, reducing overall side effect risks.”
  • Verification: Accurate. Rosemary extract is natural and potent with antioxidant, anti-inflammatory, and antimicrobial effects from compounds like carnosic acid; versatile for acne and aging concerns with synergistic potential; widely available, affordable, GRAS-approved; non-comedogenic for blemish-prone skin; and has minimal systemic effects due to limited topical absorption.
  • Citations:
    • Rosmarinus officinalis and Skin: Antioxidant Activity and Possible Therapeutical Role in Cutaneous Diseases. (2023). Antioxidants, 12(3), 680. https://doi.org/10.3390/antiox12030680
      • “Rosemary extracts have Generally Recognized as Safe (GRAS) status from the US Food and Drug Administration… Key bioactive compounds include rosmarinic acid… phenolic diterpenes (carnosic acid, carnosol… with antioxidant, anti-inflammatory…”
    • Rosmarinus officinalis L. (rosemary) as therapeutic and prophylactic agent. (2019). Journal of Biomedical Science, 26(1), 5. https://doi.org/10.1186/s12929-019-0499-8
      • “No direct toxicity or adverse effects from R. officinalis L. extracts are reported… positioned as a safe alternative to conventional medicines, equivalent in efficacy with fewer side effects.”
  1. Cons
  • Claim: “Cons: Potential Irritation: Volatile components like terpenes may cause contact dermatitis, redness, or sensitization, especially in essential oil forms. Instability: Prone to degradation from light, heat, or oxygen, requiring encapsulation for efficacy. Overuse Risk: Excessive application can dry out skin or lead to rebound irritation. Variable Quality: Commercial products may vary in concentration or include additives that reduce benefits. Limited Hydration: Not inherently moisturizing, so it should be combined with humectants for dry skin. Environmental Concerns: Potential sustainability issues from overharvesting, though cultivated sources are common.”
  • Verification: Accurate. Rosemary extract may cause irritation (e.g., contact dermatitis) from volatile terpenes, especially in essential oils; is unstable to light/heat/oxygen necessitating encapsulation; risks dryness or rebound irritation with overuse; has variable quality in commercial products; offers limited hydration requiring humectant pairing for dry skin; and raises sustainability concerns despite common cultivation.
  • Citations:
    • Rosmarinus officinalis and Skin: Antioxidant Activity and Possible Therapeutical Role in Cutaneous Diseases. (2023). Antioxidants, 12(3), 680. https://doi.org/10.3390/antiox12030680
      • “The review notes the need for further assessment of risk-benefit balance for topical use due to potential phytodermatitis… In clinical comparisons for alopecia, rosemary essential oil caused less scalp irritation than 2% minoxidil.”
    • Rosmarinus officinalis L.: an update review of its phytochemistry and biological activity. (2018). Future Science OA, 4(4), FSO283. https://doi.org/10.4155/fsoa-2017-0124
      • “Carnosic acid converts to carnosol by oxidation and has physicochemical, thermal, and photolabile properties… no comprehensive safety profile, toxicity data, or side effects specific to rosemary extract are detailed.”

 

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